Synthesis of a Human Urinary Metabolite of Prostaglandin D2.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03983
Abstract: A chemical synthesis of the major human metabolite of prostaglandin D2, tricyclic-PGDM, is described. The synthetic route starts from iodocyclopentenone 1 (available from cyclopentadiene in 6 steps) and requires 13 synthetic transformations. The synthetic route… read more here.
Keywords: metabolite prostaglandin; synthesis human; human urinary; metabolite ... See more keywords
Microheterogeneity and Individual Differences of Human Urinary N-Glycome under Normal Physiological Conditions
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DOI: 10.3390/biom13050756
Abstract: Urine is considered an outstanding biological fluid for biomarker discovery, reflecting both systemic and urogenital physiology. However, analyzing the N-glycome in urine in detail has been challenging due to the low abundance of glycans attached… read more here.
Keywords: human urinary; individual differences; differences human; urinary glycome ... See more keywords
Comparison of Human Urinary Exosomes Isolated via Ultracentrifugation Alone versus Ultracentrifugation Followed by SEC Column-Purification
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12030340
Abstract: Chronic kidney disease is a progressive, incurable condition that involves a gradual loss of kidney function. While there are no non-invasive biomarkers available to determine whether individuals are susceptible to developing chronic kidney disease, small… read more here.
Keywords: exosomal preparations; ultracentrifugation; human urinary; urinary exosomes ... See more keywords