Dose-Dependent Response to 3-Nitrobenzanthrone Exposure in Human Urothelial Cancer Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.7b00174
Abstract: A product of incomplete combustion of diesel fuel, 3-nitrobenzanthrone (3-NBA), has been classified as a cancer-causing substance. It first gained attention as a potential urinary bladder carcinogen due to the presence of its metabolite in… read more here.
Keywords: urothelial cancer; response; human urothelial; exposure ... See more keywords
Induction of p27 Contributes to Inhibitory Effect of Isorhapontigenin (ISO) on Malignant Transformation of Human Urothelial Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cell cycle"
DOI: 10.1080/15384101.2022.2074623
Abstract: Bladder cancer (BC) is the most expensive cancer to manage on a per-patient basis, costing about $4 billion in total healthcare expenditure per annum in America alone. Therefore, identifying a natural compound for prevention of… read more here.
Keywords: p27; effect; human urothelial; egf induced ... See more keywords
An immunoresponsive three-dimensional urine-tolerant human urothelial model to study urinary tract infection
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1128132
Abstract: Introduction Murine models of urinary tract infection (UTI) have improved our understanding of host-pathogen interactions. However, given differences between rodent and human bladders which may modulate host and bacterial response, including certain biomarkers, urothelial thickness… read more here.
Keywords: urinary tract; tract infection; urine tolerant; infection ... See more keywords