Articles with "human uterine" as a keyword



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Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ERα36 via nongenomic signaling pathways

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Published in 2019 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2019.01.001

Abstract: The role of ERα36 in regulating BPA's effects and its potential as a risk factor for human uterine fibroids were evaluated. BPA at low concentrations (10-6 μM - 10 μM) increased proliferation by facilitating progression of hormonally… read more here.

Keywords: nongenomic signaling; signaling pathways; proliferation; membrane associated ... See more keywords
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Mesenchymal Stem Cells Attenuate Lipopolysaccharide-Induced Inflammatory Response in Human Uterine Smooth Muscle Cells

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Published in 2020 at "AJP Reports"

DOI: 10.1055/s-0040-1715166

Abstract: Objective  The aim of this study was to determine if mesenchymal stem cells (MSCs) would suppress the inflammatory response in human uterine cells in an in vitro lipopolysaccharide (LPS)-based preterm birth (PTB) model. Study Design… read more here.

Keywords: inflammatory response; human uterine; uterine smooth; response human ... See more keywords
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Partial Reconstruction of Uterus Cervix in Rat by Decellularized Human Uterine Cervical Scaffold Combined with Adipose-Derived Stem Cells (ADSCs)

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Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/6287435

Abstract: Surgical management for cervical malformation remains as the main therapeutic challenge for gynecologists. A theoretical alternative is to generate a bioengineered uterus cervix, which requires scaffold structure and appropriate cellular constituents. Here, human uterine cervical… read more here.

Keywords: uterus cervix; adipose derived; scaffold; human uterine ... See more keywords
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Proteinase Activated Receptors Mediate the Trypsin-Induced Ca2 + Signaling in Human Uterine Epithelial Cells

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.709902

Abstract: Embryo implantation is a complex and tightly regulated process. In humans, uterine luminal epithelium functions as a biosensor gauging the embryo quality and transmitting this information to the underlying endometrial stromal cells. This quality control… read more here.

Keywords: mediate trypsin; trypsin; activated receptors; human uterine ... See more keywords
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Corrigendum: Antifungal Activity of the Human Uterine Cervical Stem Cells Conditioned Medium (hUCESC-CM) Against Candida albicans and Other Medically Relevant Species of Candida

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Published in 2019 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2019.01297

Abstract: [This corrects the article DOI: 10.3389/fmicb.2018.02818.]. read more here.

Keywords: corrigendum antifungal; activity human; uterine cervical; human uterine ... See more keywords
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E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24119606

Abstract: E7050 is an inhibitor of VEGFR2 with anti-tumor activity; however, its therapeutic mechanism remains incompletely understood. In the present study, we aim to evaluate the anti-angiogenic activity of E7050 in vitro and in vivo and… read more here.

Keywords: resistant human; vegfr2; multidrug resistant; human uterine ... See more keywords
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Report of Exosomes Isolated from a Human Uterine Leiomyoma Cell Line and Their Impact on Endometrial Vascular Endothelial Cells

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Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15050577

Abstract: Uterine leiomyomas are the most common pelvic tumor in women of reproductive age; they cause irregular heavy menstrual bleeding leading to anemia and subsequent negative effects on quality of life. Exosomes have arisen as main… read more here.

Keywords: uterine leiomyoma; cell; derived exosomes; endothelial cells ... See more keywords