Exploring biomechanical methods to study the human vaginal wall
Sign Up to like & getrecommendations! Published in 2017 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.22968
Abstract: To critically review studies of the biomechanical properties of connective tissue in the normal and prolapsed human vaginal wall and to identify criteria that are suitable for in vivo measurements which could improve patient management. read more here.
Keywords: human vaginal; biomechanical methods; methods study; exploring biomechanical ... See more keywords
Cell type-specific expression of estrogen and progesterone receptors in the human vaginal mucosa.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108874
Abstract: Female sex hormones affect the immune response in the lower female genital tract. To understand their mechanisms of action, it is essential to define cell types expressing estrogen receptor (ER) and/or progesterone receptor (PR) in… read more here.
Keywords: human vaginal; estrogen; vaginal mucosa; cell ... See more keywords
Variability of the response of human vaginal Lactobacillus crispatus to 17β-estradiol
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-91017-5
Abstract: We previously showed that the physiological concentration of 17β-estradiol in the vaginal environment is sufficient to affect the membrane dynamics and adhesion phenotype of the Lactobacillus crispatus strain CIP104459. However, L. crispatus is a heterogeneous… read more here.
Keywords: human vaginal; variability response; lactobacillus crispatus; response human ... See more keywords
Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers – antiherpes activity and penetration behavior across the human vaginal epithelium
Sign Up to like & getrecommendations! Published in 2021 at "Drug Delivery"
DOI: 10.1080/10717544.2021.1992037
Abstract: Abstract Chitosan glutamate (gCS) spray-dried microparticles appear promising carriers to overcome challenges associated with vaginal microbicide delivery. This study aimed at elucidating the penetration and mucoadhesive behavior of developed gCS multiunit carriers with zidovudine (ZVD)… read more here.
Keywords: vaginal epithelium; human vaginal; penetration; antiherpes activity ... See more keywords
Assessment of In Vitro and In Silico Protocols for Sequence-Based Characterization of the Human Vaginal Microbiome
Sign Up to like & getrecommendations! Published in 2020 at "mSphere"
DOI: 10.1128/msphere.00448-20
Abstract: The vaginal microbiome has been connected to various aspects of host health, including susceptibility to sexually transmitted infections as well as gynecological cancers and pregnancy outcomes. This has led to a thriving research environment but… read more here.
Keywords: vaginal microbiome; microbiome; characterization human; human vaginal ... See more keywords
Pathogen Stimulation of Interleukin-8 from Human Vaginal Epithelial Cells through CD40
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00106-22
Abstract: Most bacterial and fungal pathogens cause disease across mucosal, and to a lesser extent, skin barriers with the help of induced chemokines from epithelial cells. In this study, we showed that potential vaginal pathogens Staphylococcus… read more here.
Keywords: cause disease; cd40; epithelial cells; vaginal epithelial ... See more keywords
Cultivated Human Vaginal Microbiome Communities Impact Zika and Herpes Simplex Virus Replication in ex vivo Vaginal Mucosal Cultures
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.03340
Abstract: The human vaginal microbiome (VMB) is a complex bacterial community that interacts closely with vaginal epithelial cells (VECs) impacting the mucosal phenotype and its responses to pathogenic insults. The VMB and VEC relationship includes nutrient… read more here.
Keywords: human vaginal; vaginal microbiome; herpes simplex; simplex virus ... See more keywords
Interferon Epsilon Signaling Confers Attenuated Zika Replication in Human Vaginal Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11080853
Abstract: Zika virus (ZIKV) is an emerging flavivirus that causes congenital birth defects and neurological compilations in the human host. Although ZIKV is primarily transmitted through infected mosquitos, recent studies reveal sexual contact as a potential… read more here.
Keywords: interferon epsilon; replication; zikv; epithelial cells ... See more keywords