Articles with "human validated" as a keyword



Abstract 5166: Increasing translatability of syngeneic mouse models of cancer through the application of human-validated, clinically relevant gene expression-based measurements of the tumor immune microenvironment

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-5166

Abstract: Syngeneic mouse models serve as invaluable tools in preclinical research. Implanting cancer cells into immunocompetent mice allows immunotherapy responses to be assessed in a physiologically relevant setting. To further improve the translatability of syngeneic models,… read more here.

Keywords: cancer; tumor; human validated; syngeneic ... See more keywords