Human variability in isoform-specific UDP-glucuronosyltransferases: markers of acute and chronic exposure, polymorphisms and uncertainty factors
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DOI: 10.1007/s00204-020-02765-8
Abstract: UDP-glucuronosyltransferases (UGTs) are involved in phase II conjugation reactions of xenobiotics and differences in their isoform activities result in interindividual kinetic differences of UGT probe substrates. Here, extensive literature searches were performed to identify probe… read more here.
Keywords: uncertainty; uncertainty factors; isoform; probe substrates ... See more keywords
Human Variability and the Explore-Exploit Trade-Off in Recommendation
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DOI: 10.1111/cogs.13279
Abstract: The enormous scale of the available information and products on the Internet has necessitated the development of algorithms that intermediate between options and human users. These algorithms attempt to provide the user with relevant information.… read more here.
Keywords: information; algorithms; variability; exploration exploitation ... See more keywords