Microengineered Human Vein-Chip Recreates Venous Valve Architecture and Its Contribution to Thrombosis.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.202003401
Abstract: Deep vein thrombosis (DVT) and its consequences are lethal, but current models cannot completely dissect its determinants-endothelium, flow, and blood constituents-together called Virchow's triad. Most models for studying DVT forego assessment of venous valves that… read more here.
Keywords: human vein; vein chip; thrombosis; microengineered human ... See more keywords
Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103954
Abstract: Summary Background Intimal hyperplasia (IH) remains a major limitation in the long-term success of any type of revascularisation. IH is due to vascular smooth muscle cell (VSMC) dedifferentiation, proliferation and migration. The gasotransmitter Hydrogen Sulfide… read more here.
Keywords: hydrogen sulfide; vein segments; human vein; sodium thiosulfate ... See more keywords
Evidence for cytostatic effect of cyclophosphamide on human vein endothelial cells in cancer therapy: Preliminary in vitro results.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical hemorheology and microcirculation"
DOI: 10.3233/ch-189125
Abstract: In cancer therapy, a number of drugs with different mechanisms of action are in clinical use, which act directly after administration without metabolism, while others only become active in the metabolites produced in the liver.… read more here.
Keywords: human vein; vein endothelial; endothelial cells; therapy ... See more keywords