Targeting the PD-1/PD-L1 Axis in Human Vitiligo
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DOI: 10.3389/fimmu.2020.579022
Abstract: Autoreactive CD8+ T cells play a pivotal role in melanocyte destruction in autoimmune vitiligo. Immunotherapy for melanoma often leads to autoimmune side-effects, among which vitiligo-like depigmentation, indicating that targeting immune checkpoints can break peripheral tolerance… read more here.
Keywords: axis human; targeting axis; human vitiligo;