Articles with "human wharton" as a keyword



Micro‐vesicles derived from human Wharton's Jelly mesenchymal stromal cells mitigate renal ischemia‐reperfusion injury in rats after cardiac death renal transplantation

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Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26348

Abstract: The purpose of the present study was to investigate the possible therapeutic effects of the human Wharton‐Jelly mesenchymal stromal cells derived micro‐vesicles (hWJMSCs‐MVs) on renal ischemia‐reperfusion injury (IRI) after cardiac death (CD) renal transplantation in… read more here.

Keywords: mesenchymal stromal; renal transplantation; wharton jelly; jelly mesenchymal ... See more keywords

Spidroin striped micropattern promotes chondrogenic differentiation of human Wharton’s jelly mesenchymal stem cells

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Published in 2022 at "Scientific Reports"

DOI: 10.1038/s41598-022-08982-8

Abstract: Cartilage tissue engineering, particularly micropattern, can influence the biophysical properties of mesenchymal stem cells (MSCs) leading to chondrogenesis. In this research, human Wharton’s jelly MSCs (hWJ-MSCs) were grown on a striped micropattern containing spider silk… read more here.

Keywords: wharton jelly; striped micropattern; stem cells; human wharton ... See more keywords

Proteomic analysis of human Wharton’s jelly mesenchymal stem/stromal cells and human amniotic epithelial stem cells: a comparison of therapeutic potential

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Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-79063-1

Abstract: Perinatal stem cells have prominent applications in cell therapy and regenerative medicine. Among them, human Wharton’s jelly mesenchymal stem/stromal cells (hWJMSCs) and human amniotic epithelial stem cells (hAESCs) have been widely used. However, the distinction… read more here.

Keywords: therapeutic potential; stem; stem cells; wharton jelly ... See more keywords
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The effect of allogenic human Wharton's jelly stem cells seeded onto acellular dermal matrix in healing of rat burn wounds

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Published in 2019 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.13109

Abstract: Various methods were introduced to overcome the autograft shortage in burn wound care, including cell transplantation and tissue engineering. read more here.

Keywords: allogenic human; burn; effect allogenic; wharton jelly ... See more keywords

Fabrication of 3D Collagen-Based Decellularized Biological Scaffolds Using Human Wharton's Jelly-Derived Mesenchymal Stem Cells With Differentiation Potential Toward Chondrocytes

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Published in 2025 at "Stem Cells International"

DOI: 10.1155/sci/9953810

Abstract: Background: Stem cell-based regenerative approaches have been developed to treat osteoarthritis (OA) and repair cartilage defects. In the present study, we fabricated a three-dimensional (3D) collagen-based decellularized biological scaffold using human Wharton's jelly-derived mesenchymal stem… read more here.

Keywords: collagen; stem; collagen based; stem cells ... See more keywords

Mesenchymal Stromal Cells from Human Wharton’s Jelly Modulate the Intraocular Immune Response in a Glucocorticoid Hypertension Model: An Exploratory Analysis

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Published in 2024 at "Ophthalmic Research"

DOI: 10.1159/000538183

Abstract: Abstract Introduction: Glaucoma is a neurodegenerative disease characterized by the loss of retinal ganglion cells. Recent research suggests immunological changes such as cytokine imbalance may affect its pathophysiology. This implies that immunomodulation, like that of… read more here.

Keywords: hwj mscs; mesenchymal stromal; stromal cells; wharton jelly ... See more keywords

Transplantation of Exosomes Derived From Human Wharton’s Jelly Mesenchymal Stromal Cells Enhances Functional Improvement in Stroke Rats

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Published in 2024 at "Cell Transplantation"

DOI: 10.1177/09636897241296366

Abstract: Cerebral ischemic stroke is a major cerebrovascular disease and the leading cause of adult disability. We and others previously demonstrated that transplantation of human Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) attenuated neuronal damage and promoted… read more here.

Keywords: improvement; mesenchymal stromal; wharton jelly; human wharton ... See more keywords

Signaling Pathways Impact on Induction of Corneal Epithelial-like Cells Derived from Human Wharton’s Jelly Mesenchymal Stem Cells

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23063078

Abstract: Corneal epithelium, the outmost layer of the cornea, comprises corneal epithelial cells (CECs) that are continuously renewed by limbal epithelial stem cells (LESCs). Loss or dysfunction of LESCs causes limbal stem cell deficiency (LSCD) which… read more here.

Keywords: human wharton; corneal epithelial; mesenchymal stem; stem ... See more keywords

Cytochalasin B Influences Cytoskeletal Organization and Osteogenic Potential of Human Wharton’s Jelly Mesenchymal Stem Cells

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Published in 2023 at "Pharmaceuticals"

DOI: 10.3390/ph16020289

Abstract: Among perinatal stem cells of the umbilical cord, human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) are of great interest for cell-based therapy approaches in regenerative medicine, showing some advantages over other MSCs. In fact, hWJ-MSCs,… read more here.

Keywords: human wharton; cytoskeletal organization; stem; stem cells ... See more keywords

Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology

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Published in 2022 at "World Journal of Stem Cells"

DOI: 10.4252/wjsc.v14.i5.347

Abstract: BACKGROUND Human Wharton’s jelly-derived mesenchymal stromal/stem cells (hWJ-MSCs) have gained considerable attention in their applications in cell-based therapy due to several advantages offered by them. Recently, we reported that hWJ-MSCs and their conditioned medium have… read more here.

Keywords: human wharton; network; radioprotection; stem ... See more keywords