Humanization of Chicken‐Derived scFv Using Yeast Surface Display and NGS Data Mining
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Journal"
DOI: 10.1002/biot.202000231
Abstract: Generation of high‐affinity monoclonal antibodies by immunization of chickens is a valuable strategy, particularly for obtaining antibodies directed against epitopes that are conserved in mammals. A generic procedure is established for the humanization of chicken‐derived… read more here.
Keywords: affinity; yeast surface; chicken; humanization ... See more keywords
Meta-humanization reduces prejudice, even under high intergroup threat.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of personality and social psychology"
DOI: 10.1037/pspi0000259
Abstract: Meta-dehumanization, the perception your group has been given less than human qualities, contributes to a vicious cycle of outgroup dehumanization and hostility, such as hate crimes and support for discriminatory policies. Minimal research has investigated… read more here.
Keywords: indirect effect; meta humanization; intergroup; threat ... See more keywords
Today´s medical self and the other: Challenges and evolving solutions for enhanced humanization and quality of care
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0181514
Abstract: Background Recent scientific developments, along with growing awareness of cultural and social diversity, have led to a continuously growing range of available treatment options; however, such developments occasionally lead to an undesirable imbalance between science,… read more here.
Keywords: medicine; clinical practice; today medical; humanization ... See more keywords
From humanitarian aid to humanization: When outgroup, but not ingroup, helping increases humanization
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0207343
Abstract: Dehumanization and infrahumanization involve decreasing the humanity attributed to others. Despite the existence of a large body of work on these topics, little is known about how to increase outgroup humanization. Across two experiments, we… read more here.
Keywords: infrahumanization; dehumanization; outgroup ingroup; ingroup helping ... See more keywords
Priming attachment security and outgroup humanization: The mediation role of intergroup emotions
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0265714
Abstract: Individuals tend to dehumanize the outgroup. In this paper, we explore whether the activation of attachment security can attenuate dehumanization. Two studies were performed. In Study 1, attachment security was primed by showing pictures that… read more here.
Keywords: outgroup humanization; attachment security; security; intergroup emotions ... See more keywords
Women's perception of labor and birth care: obstacles to humanization.
Sign Up to like & getrecommendations! Published in 2022 at "Revista brasileira de enfermagem"
DOI: 10.1590/0034-7167-2021-0215
Abstract: OBJECTIVES to understand women's perception regarding the care received during labor and birth. METHODS this is a descriptive-exploratory, qualitative study carried out with 54 postpartum women from hospitals in the Metropolitan Region II of the… read more here.
Keywords: labor birth; care; birth; women perception ... See more keywords
Humanization and characterization of a murine monoclonal neutralizing antibody against human adenovirus 7.
Sign Up to like & getrecommendations! Published in 2023 at "Virology"
DOI: 10.2139/ssrn.4352953
Abstract: Human adenovirus type 7 (HAdV7) is commonly associated with febrile acute respiratory disease (ARD) outbreaks. We have reported that 10G12, a mouse monoclonal antibody (mAb) specifically recognizing and neutralizing HAdV7, is a promising candidate for… read more here.
Keywords: human adenovirus; humanization characterization; characterization murine; antibody ... See more keywords
The influence of antibody humanization on shark variable domain (VNAR) binding site ensembles
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.953917
Abstract: Sharks and other cartilaginous fish produce new antigen receptor (IgNAR) antibodies, as key part of their humoral immune response and are the phylogenetically oldest living organisms that possess an immunoglobulin (Ig)-based adaptive immune system. IgNAR… read more here.
Keywords: binding site; antibody humanization; vnar; humanization ... See more keywords
Humanization and expression of IgG and IgM antibodies in plants as potential diagnostic reagents for Valley Fever
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.925008
Abstract: Monoclonal antibodies (mAbs) are important proteins used in many life science applications, from diagnostics to therapeutics. High demand for mAbs for different applications urges the development of rapid and reliable recombinant production platforms. Plants provide… read more here.
Keywords: humanization; valley fever; expression; igg igm ... See more keywords
Engineering an Enhanced EGFR Engager: Humanization of Cetuximab for Improved Developability
Sign Up to like & getrecommendations! Published in 2022 at "Antibodies"
DOI: 10.3390/antib11010006
Abstract: The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase whose proliferative effects can contribute to the development of many types of solid tumors when overexpressed. For this reason, EGFR inhibitors such as cetuximab… read more here.
Keywords: egfr engager; engineering enhanced; cetuximab; enhanced egfr ... See more keywords
In Situ “Humanization” of Porcine Bioprostheses: Demonstration of Tendon Bioprostheses Conversion into Human ACL and Possible Implications for Heart Valve Bioprostheses
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineering"
DOI: 10.3390/bioengineering8010010
Abstract: This review describes the first studies on successful conversion of porcine soft-tissue bioprostheses into viable permanently functional tissue in humans. This process includes gradual degradation of the porcine tissue, with concomitant neo-vascularization and reconstruction of… read more here.
Keywords: tissue; porcine; humanization; acl ... See more keywords