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Recombinant Humanized IgG1 Antibody Protects against oxLDL-Induced Oxidative Stress and Apoptosis in Human Monocyte/Macrophage THP-1 Cells by Upregulation of MSRA via Sirt1-FOXO1 Axis

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231911718

Abstract: Oxidized low-density lipoprotein (oxLDL)-induced oxidative stress and apoptosis are considered as critical contributors to cardiovascular diseases. Methionine sulfoxide reductase A (MSRA) is a potent intracellular oxidoreductase and serves as an essential factor that protects cells… read more here.

Keywords: oxidative stress; recombinant humanized; humanized igg1; msra ... See more keywords