Development of humanized scFv antibody fragment(s) that targets and blocks specific HLA alleles linked to myasthenia gravis
Sign Up to like & getrecommendations! Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8557-1
Abstract: Myasthenia gravis (MG) is an autoimmune disease caused by sensitization of the immune system to self-antigens. We have previously shown that targeting MG-susceptible alleles can significantly inhibit proliferation of disease-specific T cells. In this work,… read more here.
Keywords: humanized scfv; antibody; hla; scfv ... See more keywords
Development and in vitro characterization of a humanized scFv against fungal infections
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DOI: 10.1371/journal.pone.0276786
Abstract: The resistance and the birth of new intrinsic and multidrug-resistant pathogenic species like C. auris is creating great concern in the antifungal world. Given the limited drug arsenal and the lack of effectiveness of the… read more here.
Keywords: characterization humanized; vitro characterization; development vitro; scfv fungal ... See more keywords