Articles with "humans rats" as a keyword



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Species differences in liver microsomal hydrolysis of acyl glucuronide in humans and rats

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Published in 2022 at "Xenobiotica"

DOI: 10.1080/00498254.2022.2131484

Abstract: Abstract Acyl glucuronides (AGs) are known as one of the causes of idiosyncratic drug toxicity (IDT). Although AGs can be enzymatically hydrolysed by β-glucuronidase and esterase, much information on their characteristics and species differences is… read more here.

Keywords: species differences; humans rats; acyl; hydrolysis ... See more keywords