Humoral Responses Against Variants of Concern by COVID-19 mRNA Vaccines in Immunocompromised Patients
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2022.0446
Abstract: Key Points Question Are there differences in the magnitude and durability of neutralizing antibody (nAb) responses against SARS-CoV-2 variants of concern (VOCs) according to the mRNA-1273 (Moderna) and BNT162b2 (Pfizer-BioNTech) vaccines? Findings In this comparative… read more here.
Keywords: mrna; variants concern; immunocompromised patients; nab responses ... See more keywords
SARS‐CoV‐2 humoral responses following booster BNT162b2 vaccination in patients with B‐cell malignancies
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26669
Abstract: Patients with B‐cell malignancies have suboptimal immune responses to SARS‐CoV‐2 vaccination and are a high‐risk population for severe COVID19 disease. We evaluated the effect of a third booster BNT162b2 vaccine on the kinetics of anti‐… read more here.
Keywords: patients cell; booster bnt162b2; cell malignancies; humoral responses ... See more keywords
Risk of waning humoral responses after inactivated or subunit recombinant SARS‐CoV‐2 vaccination in patients with chronic diseases: Findings from a prospective observational study in China
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28434
Abstract: Heterogeneity of antibody responses has been reported in SARS‐CoV‐2 vaccination recipients with underlying diseases. We investigated the impact of the presence of comorbidities on the humoral response to SARS‐CoV‐2 vaccination in patients with chronic disease… read more here.
Keywords: vaccination; subunit recombinant; cov vaccination; humoral responses ... See more keywords
Immune priming in shellfish: A review and an updating mechanistic insight focused on cellular and humoral responses
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DOI: 10.1016/j.aquaculture.2020.735831
Abstract: Abstract Immune priming has now been demonstrated as a form of immune memory in a wide range of invertebrate species that lack acquired immune systems. Owing to the specific activation of innate immunity upon reinfection,… read more here.
Keywords: focused cellular; humoral responses; shellfish review; immune priming ... See more keywords
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.11.004
Abstract: T follicular helper (Tfh) cells are essential for the establishment, maintenance and output of the germinal centre (GC) response. The transient nature of this response, and its location within secondary lymphoid tissues have hampered our… read more here.
Keywords: humoral responses; impact humoral; helper cells; helper ... See more keywords
Long-term immunological consequences of anti-CD20 therapies on humoral responses to COVID-19 vaccines in multiple sclerosis: an observational study
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Neurological Disorders"
DOI: 10.1177/17562864221092092
Abstract: Background: Anti-CD20 therapies induce pronounced B-cell depletion and blunt humoral responses to vaccines. Recovery kinetics of anti-CD20 therapy-mediated cellular and humoral effects in people with multiple sclerosis (pwMS) are poorly defined. Objective: To investigate the… read more here.
Keywords: cell; anti cd20; covid vaccines; responses covid ... See more keywords
Humoral responses to SARS-CoV-2 by healthy and sick dogs during the COVID-19 pandemic in Spain
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary Research"
DOI: 10.1186/s13567-021-00897-y
Abstract: COVID-19 is a zoonotic disease caused by SARS-CoV-2. Infections of animals with SARS-CoV-2 have recently been reported, and an increase of severe lung pathologies in domestic dogs has also been detected by veterinarians in Spain.… read more here.
Keywords: cov healthy; healthy sick; responses sars; sick dogs ... See more keywords
Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform
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DOI: 10.1371/journal.pone.0196950
Abstract: Safe and efficacious orally-delivered mucosal vaccine platforms are desperately needed to combat the plethora of mucosally transmitted pathogens. Lactobacillus spp. have emerged as attractive candidates to meet this need and are known to activate the… read more here.
Keywords: vaccine; humoral responses; vaccine platform; antigen specific ... See more keywords
Virological and Clinical Determinants of the Magnitude of Humoral Responses to SARS-CoV-2 in Mild-Symptomatic Individuals
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.860215
Abstract: Background Evidence on the determinants of the magnitude of humoral responses and neutralizing titers in individuals with mild COVID-19 is scarce. Methods In this cohort study of mild COVID-19 patients, we assessed viral load (VL)… read more here.
Keywords: determinants magnitude; virological clinical; magnitude humoral; clinical determinants ... See more keywords
Cellular and humoral responses after second and third SARS-CoV-2 vaccinations in patients with autoimmune diseases treated with rituximab: specific T cell immunity remains longer and plays a protective role against SARS-CoV-2 reinfections
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1146841
Abstract: Background Humoral and cellular immune responses are known to be crucial for patients to recover from COVID-19 and to protect them against SARS-CoV-2 reinfection once infected or vaccinated. Objectives This study aimed to investigate humoral… read more here.
Keywords: cell; autoimmune diseases; patients autoimmune; second third ... See more keywords
Longitudinal SARS-CoV-2 humoral response in MS patients with and without SARS-CoV-2 infection prior to vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.1032830
Abstract: Introduction During the COVID-19 pandemic, certain disease modifying therapies (DMTs) used in multiple sclerosis (MS), such as anti-CD20 therapies, have been associated with decreased humoral responses after SARS-CoV-2 vaccination. Hybrid immunity, referring to immunity after… read more here.
Keywords: vaccination; cov infection; humoral responses; sars cov ... See more keywords