Machine Learning and Imputation to Characterize Human Norovirus Genotype Susceptibility to Sodium Hypochlorite
Sign Up to like & getrecommendations! Published in 2024 at "Food and Environmental Virology"
DOI: 10.1007/s12560-024-09613-3
Abstract: Human norovirus (HuNoV) is the leading cause of foodborne illness in the developed world and a major contributor to gastroenteritis globally. Its low infectious dose and environmental persistence necessitate effective disinfection protocols. Sodium hypochlorite (NaOCl)… read more here.
Keywords: human norovirus; susceptibility; hunov; machine learning ... See more keywords
A Luciferase Immunoprecipitation System (LIPS) assay for profiling human norovirus antibodies.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2017.06.017
Abstract: A luciferase immunoprecipitation systems (LIPS) assay was developed to define the antigenic specificity and titer of antibodies directed against human norovirus (HuNoV). Recombinant proteins, expressed by plasmid constructs encoding Renilla luciferase (Ruc) fused to the… read more here.
Keywords: luciferase immunoprecipitation; lips assay; hunov; human norovirus ... See more keywords
Human intestinal organoids express histo-blood group antigens, bind norovirus VLPs, and support limited norovirus replication
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12736-2
Abstract: Through pluripotent stem cell (PSC) technology, human intestinal organoids (HIOs) with remarkably similarity to the fetal intestine in cellular composition, architecture, and absorptive/secretory functions have been successfully developed, providing a useful in vitro model system… read more here.
Keywords: organoids express; replication human; human intestinal; intestinal organoids ... See more keywords
Protective Effect of Select Bacterial Species Representative of Fresh Produce on Human Norovirus Surrogates Exposed to Disinfecting Pulsed Light
Sign Up to like & getrecommendations! Published in 2023 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00043-23
Abstract: Recent studies have shown that bacteria may be involved in the attachment of HuNoV to the surface of fresh produce. Because these foods are difficult to disinfect by conventional methods without compromising product quality, nonthermal… read more here.
Keywords: hunov; fresh produce; disinfecting pulsed; biofilm ... See more keywords
Hybrid paper/PDMS microfluidic device integrated with RNA extraction and recombinase polymerase amplification for detection of norovirus in foods
Sign Up to like & getrecommendations! Published in 2024 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01208-24
Abstract: ABSTRACT Human norovirus (HuNoV) is recognized as the leading causative agent of foodborne outbreaks of epidemic gastroenteritis. Consequently, there is a high demand for developing point-of-care testing for HuNoV. We developed an origami microfluidic device… read more here.
Keywords: detection; food; hunov; microfluidic device ... See more keywords
Antiviral Activity of Olanexidine-Containing Hand Rub against Human Noroviruses
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02848-21
Abstract: Human noroviruses (HuNoVs) are highly contagious and cause nonbacterial acute gastroenteritis in all age groups worldwide. Since the introduction of rotavirus vaccines, HuNoVs have become the leading cause of diarrheal illness in children. ABSTRACT Human… read more here.
Keywords: hand; hunov; hand rub; cause ... See more keywords
Insights into human norovirus cultivation in human intestinal enteroids
Sign Up to like & getrecommendations! Published in 2024 at "mSphere"
DOI: 10.1128/msphere.00448-24
Abstract: ABSTRACT Human noroviruses (HuNoVs) are a significant cause of epidemic and sporadic acute gastroenteritis worldwide. The lack of a reproducible culture system hindered the study of HuNoV replication and pathogenesis for almost a half-century. This… read more here.
Keywords: hunov replication; hunov; human intestinal; culture ... See more keywords
The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03157-22
Abstract: Despite causing over 700 million infections yearly, many gaps remain in the knowledge of human norovirus (HuNoV) biology due to an historical lack of efficient cultivation systems. Fucose-containing carbohydrate structures, named histo-blood group antigens, are… read more here.
Keywords: hunov; zebrafish larvae; replication; histo blood ... See more keywords
Prevalence of Foodborne Viruses in Berries Harvested in Canada
Sign Up to like & getrecommendations! Published in 2023 at "Foods"
DOI: 10.3390/foods12040723
Abstract: It is known that the transmission of different foodborne viruses can occur either via discharge of contaminated water close to the production environment or via close contact with animal feces. Cranberries are intimately associated with… read more here.
Keywords: harvested canada; hunov; viruses berries; prevalence ... See more keywords
Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v11050444
Abstract: Human norovirus (HuNoV) is responsible for more than 95% of outbreaks of acute nonbacterial gastroenteritis worldwide. Despite major efforts, there are no vaccines or effective therapeutic interventions against this virus. Chicken immunoglobulin Y (IgY)-based passive… read more here.
Keywords: protein; hunov; specific igy; human norovirus ... See more keywords
Glycan Recognition in Human Norovirus Infections
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13102066
Abstract: Recognition of cell-surface glycans is an important step in the attachment of several viruses to susceptible host cells. The molecular basis of glycan interactions and their functional consequences are well studied for human norovirus (HuNoV),… read more here.
Keywords: human norovirus; recognition human; recognition; glycan recognition ... See more keywords