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Published in 2020 at "Acta histochemica"
DOI: 10.1016/j.acthis.2020.151650
Abstract: Huntingtin-associated protein 1 (HAP1) is a neuronal cytoplasmic protein that is predominantly expressed in the brain and spinal cord. In addition to the central nervous system, HAP1 is also expressed in the peripheral organs including…
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Keywords:
protein;
associated protein;
huntingtin associated;
hap1 ... See more keywords
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Published in 2022 at "Journal of Huntington's Disease"
DOI: 10.3233/jhd-220543
Abstract: Since the discovery of the mutation causing Huntington’s disease (HD) in 1993, it has been debated whether an expanded polyglutamine (polyQ) stretch affects the properties of the huntingtin (HTT) protein and thus contributes to the…
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Keywords:
hap40;
htt;
disease;
huntingtin associated ... See more keywords
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Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13020258
Abstract: Huntingtin-associated protein 1 (HAP1) is a determinant marker for the stigmoid body (STB), a neurocytoplasmic physiological inclusion. STB/HAP1 enriched areas in the brain/spinal cord are usually protected from neurodegenerative diseases, whereas the regions with tiny…
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Keywords:
hap1;
huntingtin associated;
lingual ganglia;
immunohistochemical distribution ... See more keywords