Sex‐specific effects of the Huntington gene on normal neurodevelopment
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.23980
Abstract: Huntington disease is a neurodegenerative disorder caused by a gene (HTT) with a unique feature of trinucleotide repeats ranging from 10 to 35 in healthy people; when expanded beyond 39 repeats, Huntington disease develops. Animal… read more here.
Keywords: specific effects; huntington gene; sex specific; gene ... See more keywords
Activity Behaviour of Minipigs Transgenic for the Huntington Gene.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Huntington's disease"
DOI: 10.3233/jhd-180325
Abstract: BACKGROUND To increase the reliability of translating preclinical findings to humans, large animal models, such as the transgenic (tg) Libechov minipig, were established. As minipigs possess high genetic homology with humans and have similarities in… read more here.
Keywords: transgenic huntington; huntington gene; activity; minipigs transgenic ... See more keywords