High cytoplasmic HuR expression is associated with advanced pT stage, high grade and increased microvessel density in urothelial bladder carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2017.12.002
Abstract: PURPOSE HuR (human antigen R) protein is a RNA binding protein that stabilizes the mRNA and controls the translation of genes involved in cell proliferation, differentiation, and carcinogenesis. Overexpression of HuR was reported in a… read more here.
Keywords: hur; mvd; hur expression; expression ... See more keywords
Cytoplasmic HuR Expression Enhances Chemoresistance in Pleural Mesothelioma Through Increased Expression of CALB2, Promotion of the E2F Pathway, and Suppression of the p53 Pathway
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DOI: 10.1111/1759-7714.70062
Abstract: Chemotherapy is crucial for treating pleural mesothelioma; however, the outcomes are poor, necessitating an urgent need to study the mechanism of chemotherapy resistance in mesothelioma cells. Human antigen R (HuR), an RNA‐binding protein and key… read more here.
Keywords: cytoplasmic hur; mesothelioma; hur expression; pleural mesothelioma ... See more keywords
Relationships between anticancer effects and serum gemcitabine levels, human antigen-R expression, and their combination in advanced urothelial cancer treated with gemcitabine and platinum agents.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.7_suppl.445
Abstract: 445 Background: Combination therapy of gemcitabine (GEM) and platinum agents and immune-checkpoint inhibitors are standard regimens for advanced urothelial carcinoma (UC), and optimum selection is important to improve the prognosis. Human antigen R (HuR) increases… read more here.
Keywords: expression; hur expression; combination; cancer ... See more keywords