Predicting the metabolic characteristics of neorudin, a novel anticoagulant fusion protein, in patients with deep vein thrombosis.
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis research"
DOI: 10.1016/j.thromres.2020.05.048
Abstract: INTRODUCTION Recombinant neorudin (EPR-hirudin, EH) is an inactive prodrug that is converted to its active metabolite, hirudin variant 2-Lys47 (HV2), at the thrombus site. We aimed to investigate the mechanism underlying site-selective bioconversion of EH… read more here.
Keywords: hv2 thrombus; hv2; site; patients deep ... See more keywords
Forensic evaluation of mitochondrial DNA heteroplasmy in Gujarat population, India
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Human Biology"
DOI: 10.1080/03014460.2022.2144447
Abstract: Abstract Background Owing to its high copy number and its small size, mtDNA analysis is the most reliable choice when biological materials from crime scenes are degraded or have mixed STR profiles. Aim To examine… read more here.
Keywords: gujarat population; heteroplasmy; mitochondrial dna; population ... See more keywords