Investigating the contribution of hyaluronan to the breast tumour microenvironment using multiparametric MRI and MR elastography.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13437
Abstract: Hyaluronan (HA) is a key component of the dense extracellular matrix in breast cancer, and its accumulation is associated with poor prognosis and metastasis. Pegvorhyaluronidase alfa (PEGPH20) enzymatically degrades HA and can enhance drug delivery… read more here.
Keywords: contribution hyaluronan; elastography; breast tumour; investigating contribution ... See more keywords
Expression and Characterization of Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization: HYBID, Alias KIAA1199 and CEMIP.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0430-4_13
Abstract: Hyaluronan (HA), a major component of the extracellular matrix in vertebrate tissues, provides structural and functional integrity to cells and organs. Biological functions of HA are dependent on the molecular size of HA and the… read more here.
Keywords: depolymerization; hyaluronan binding; hyaluronan; hybid ... See more keywords
Detection of Glycosaminoglycans in Pancreatic Islets and Lymphoid Tissues.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1398-6_53
Abstract: In this chapter, we describe the detection of the glycosaminoglycans hyaluronan and heparan sulfate in pancreatic islets and lymphoid tissues. The identification of hyaluronan in tissues is achieved by utilizing a highly specific hyaluronan binding… read more here.
Keywords: detection glycosaminoglycans; hyaluronan; heparan sulfate; tissue ... See more keywords
La protéine TSG-6 induite par l’inflammation contribue au maintien de l’hyaluronan dans l’épiderme humain
Sign Up to like & getrecommendations! Published in 2020 at "Annales De Dermatologie Et De Venereologie"
DOI: 10.1016/j.annder.2020.08.012
Abstract: TSG-6 est une proteine anti-inflammatoire impliquee dans le remodelage de la matrice extracellulaire. Cette proteine lie l’hyaluronan (HA), le principal glycosaminoglycan present dans les espaces intercellulaires des keratinocytes epidermiques. Dans les epidermes humains reconstruits (RHE) en… read more here.
Keywords: proteine; maintien; tsg; hyaluronan ... See more keywords
Regulation of hyaluronan production by β2 adrenergic receptor signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.08.056
Abstract: BACKGROUND Hyaluronan (HA), the main component of the extracellular matrix, is involved in tissue elasticity and cell scaffolding, and in progression of conditions such as cancer, inflammation and wound healing. Signaling by G protein coupled… read more here.
Keywords: production; hyaluronan; production adrenergic; activation ... See more keywords
Sequential one-pot multienzyme synthesis of hyaluronan and its derivative.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2017.09.041
Abstract: Hyaluronan (HA) is a linear polysaccharide composed of repeating disaccharide units. It has been well documented to play an array of biological functions in cancer events. Here, we reported a sequential one-pot multienzyme (OPME) strategy… read more here.
Keywords: pot; pot multienzyme; hyaluronan; one pot ... See more keywords
The behaviour of hyaluronan solutions in the presence of Hofmeister ions: A light scattering, viscometry and surface tension study.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.02.032
Abstract: Dynamic light scattering (DLS), viscosity and surface tension (SFT) measurements were used to characterize influence of salts containing ions of Hofmeister series (Na2SO4, (NH4)2SO4, NaSCN, NH4SCN and NaCl) on the behaviour of hyaluronan in diluted… read more here.
Keywords: surface tension; light scattering; hyaluronan; behaviour hyaluronan ... See more keywords
Essential hyaluronan structure for binding with hyaluronan-binding protein (HABP) determined by glycotechnological approach.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.116989
Abstract: Hyaluronan specifically binds to aggrecan globular domain 1, which is often referred to as just hyaluronan binding protein (HABP), however, the hyaluronan carbohydrate structure recognized by HABP had not been studied in detail. The aim… read more here.
Keywords: hyaluronan binding; hyaluronan; binding protein; structure ... See more keywords
SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103861
Abstract: Background Since late 2019, SARS-CoV-2 infection has resulted in COVID-19 accompanied by diverse clinical manifestations. However, the underlying mechanism of how SARS-CoV-2 interacts with host and develops multiple symptoms is largely unexplored. Methods Bioinformatics analysis… read more here.
Keywords: sars cov; sequence; hyaluronan; rna elements ... See more keywords
On the demixing of hyaluronan and alginate in the gel state.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2016.11.017
Abstract: The manuscript focuses on the demixing of hyaluronan and alginate in the hydrogel state. Binary solutions of the two polysaccharides have been treated with Ca2+ as the alginate cross-linking ion and the radial distribution of… read more here.
Keywords: alginate; state; hyaluronan; gel ... See more keywords
Hyaluronan Receptor LYVE‐1‐Expressing Macrophages Maintain Arterial Tone through Hyaluronan‐Mediated Regulation of Smooth Muscle Cell Collagen
Sign Up to like & getrecommendations! Published in 2018 at "Immunity"
DOI: 10.1016/j.immuni.2018.06.008
Abstract: SUMMARY The maintenance of appropriate arterial tone is critically important for normal physiological arterial function. However, the cellular and molecular mechanisms remain poorly defined. Here, we have shown that in the mouse aorta, resident macrophages… read more here.
Keywords: collagen; arterial tone; hyaluronan; lyve ... See more keywords