Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3‐induced mitophagy
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DOI: 10.1002/cam4.2389
Abstract: Neuroblastoma is the second most common pediatric malignancy and has a high rate of spontaneous remission. Uncovering the mechanisms underlying neuroblastoma cell differentiation is critical for therapeutic purposes. A neuroblastoma cell line (N2a) treated with… read more here.
Keywords: hyaluronan synthase; cell differentiation; differentiation; neuroblastoma cell ... See more keywords
Biosynthesis of Hyaluronic acid polymer: Dissecting the role of sub structural elements of hyaluronan synthase
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DOI: 10.1038/s41598-019-48878-8
Abstract: Hyaluronic acid (HA) based biomaterials have several biomedical applications. HA biosynthesis is catalysed by hyaluronan synthase (HAS). The unavailability of 3-D structure of HAS and gaps in molecular understanding of HA biosynthesis process pose challenges… read more here.
Keywords: hyaluronan synthase; biosynthesis; polymer; sub structural ... See more keywords