Association Between Pharmaceutical Industry Marketing Payments to Physicians and Intra-articular Hyaluronic Acid Administration to Medicare Beneficiaries.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.7018
Abstract: This cross-sectional study assesses the physician and financial factors associated with the use of hyaluronic acid to treat knee osteoarthritis. read more here.
Keywords: marketing payments; association pharmaceutical; industry marketing; pharmaceutical industry ... See more keywords
Hyaluronic Acid Microgels Modulate Inflammation and Key Matrix Molecules toward a Regenerative Signature in the Injured Annulus Fibrosus
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700077
Abstract: Low back pain results from disc degeneration, which is a chronic inflammatory disease characterized by an imbalance between anabolic and catabolic factors. Today, regenerative medicine is focused on identifying inflammatory markers to target disc disease.… read more here.
Keywords: anti inflammatory; matrix; annulus fibrosus; hyaluronic acid ... See more keywords
Covalently adaptable elastin-like protein - hyaluronic acid (ELP - HA) hybrid hydrogels with secondary thermoresponsive crosslinking for injectable stem cell delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced functional materials"
DOI: 10.1002/adfm.201605609
Abstract: Shear-thinning, self-healing hydrogels are promising vehicles for therapeutic cargo delivery due to their ability to be injected using minimally invasive surgical procedures. We present an injectable hydrogel using a novel combination of dynamic covalent crosslinking… read more here.
Keywords: like protein; elp; elastin like; hyaluronic acid ... See more keywords
Oligoethyleneimine‐Conjugated Hyaluronic Acid Modulates Inflammatory Responses and Enhances Therapeutic Efficacy for Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202100548
Abstract: Modulation of innate immune responses is a potential strategy for treating inflammatory diseases. Although biogenic polyamines are known as immunomodulatory compounds possessing anti‐inflammatory functions, their biomedical applications have been limited owing to their cytotoxicity. Here,… read more here.
Keywords: therapeutic efficacy; hyaluronic acid; inflammatory responses; ulcerative colitis ... See more keywords
Reinforced Hyaluronic Acid‐Based Matrices Promote 3D Neuronal Network Formation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201826
Abstract: 3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models. A challenge to establish 3D neuron culture models is the low elastic modulus (30–500 Pa) of… read more here.
Keywords: network formation; acid based; reinforced hyaluronic; hyaluronic acid ... See more keywords
Hyaluronic acid-based bioconjugate systems, scaffolds and their therapeutic potential.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203104
Abstract: In recent years, the development of hyaluronic acid or hyaluronan (HA) based scaffolds, medical devices, bioconjugate systems have expanded into a broad range of research and clinical applications. Research findings over the last two decades… read more here.
Keywords: systems scaffolds; scaffolds therapeutic; acid based; hyaluronic acid ... See more keywords
Glioblastoma Spheroid Invasion through Soft, Brain‐Like Matrices Depends on Hyaluronic Acid–CD44 Interactions
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202203143
Abstract: Increased secretion of hyaluronic acid (HA), a glycosaminoglycan abundant in the brain extracellular matrix (ECM), correlates with worse clinical outcomes for glioblastoma (GBM) patients. GBM cells aggressively invade the brain parenchyma while encountering spatiotemporal changes… read more here.
Keywords: cell; cd44; brain; concentration ... See more keywords
Bioactive nanofibrous structures based on hyaluronic acid
Sign Up to like & getrecommendations! Published in 2018 at "Advances in Polymer Technology"
DOI: 10.1002/adv.21851
Abstract: Studies related to selection of molar mass of hyaluronic acid and analysis of rheological properties of hyaluronic acid solutions modified with bioactive substances, used in spinning, were undertaken within the presented work. A cephalosporin group… read more here.
Keywords: structures based; nanofibrous structures; bioactive nanofibrous; hyaluronic acid ... See more keywords
Electroconductive hyaluronic acid/gelatin/poly(ethylene oxide) polymeric film reinforced by reduced graphene oxide
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.46905
Abstract: Novel electroconductive polymeric films with enhanced mechanical performance were fabricated by encapsulating reduced graphene oxide (RGO) at different concentrations (0–50 vol %) into a hyaluronic acid/gelatin/poly(ethylene oxide) (HyA/Gel/PEO) polymeric structure. The obtained RGO-reinforced polymeric films… read more here.
Keywords: graphene oxide; gelatin poly; poly ethylene; hyaluronic acid ... See more keywords
Delivery of siRNA using hyaluronic acid‐guided nanoparticles for downregulation of CXCR4
Sign Up to like & getrecommendations! Published in 2023 at "Biopolymers"
DOI: 10.1002/bip.23535
Abstract: In this study, effective transport of small interfering RNAs (siRNAs) via hyaluronic acid (HA) receptor was carried out with biodegradable HA and low‐molecular weight polyethyleneimine (PEI)‐based transport systems. Gold nanoparticles (AuNPs) capable of giving photothermal… read more here.
Keywords: sirna using; delivery sirna; sirna; cxcr4 ... See more keywords
Application of hydrocarbon and perfluorocarbon oxygen vectors to enhance heterologous production of hyaluronic acid in engineered Bacillus subtilis
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26551
Abstract: In microbial cultivations for hyaluronic acid (HA) production, oxygen can be a limiting substrate due to its poor solubility in aqueous medium and the substantial increase in culture viscosity at relatively low HA titers. Shear… read more here.
Keywords: oxygen; oxygen vectors; production; heterologous production ... See more keywords