A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis
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DOI: 10.3390/pharmaceutics14061251
Abstract: Hybrid-based drugs linked through a transition metal constitute an emerging concept for Plasmodium intervention. To advance the drug design concept and enhance the therapeutic potential of this class of drugs, we developed a novel hybrid… read more here.
Keywords: primaquine linked; amodiaquine primaquine; activity; hybrid amodiaquine ... See more keywords