Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis
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DOI: 10.1021/acs.jmedchem.1c01255
Abstract: Hybrid compounds containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids were designed with the aid of docking and molecular mechanics studies. Following the synthesis of the… read more here.
Keywords: fasudil; hybrid fasudil; multitarget; multitarget hybrid ... See more keywords