Hybrid imidazo[1,2‐a]pyridine analogs as potent ATX inhibitors with concrete in vivo antifibrosis effect
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200171
Abstract: In recent years, small‐molecule inhibitors targeting the autotaxin (ATX)/lysophosphatidic acid axis gradually brought excellent disease management benefits. Herein, a series of imidazo[1,2‐a]pyridine compounds (1–11) were designed as ATX inhibitors through a hybrid strategy by combining… read more here.
Keywords: analogs potent; hybrid imidazo; imidazo pyridine; atx inhibitors ... See more keywords