Advancing the Pharmaceutical Potential of Bioinorganic Hybrid Lipid‐Based Assemblies
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201800564
Abstract: Abstract Bioinspired lipid assemblies that mimic the elaborate architecture of natural membranes have fascinated researchers for a long time. These lipid assemblies have gone from being just an imperative platform for biophysical research to a… read more here.
Keywords: hybrid lipid; lipid based; pharmaceutical potential; bioinorganic hybrid ... See more keywords
Inhibition of the Fibrillation of Amyloid Aβ1-40 by Hybrid- lipid-Polymer Vesicles.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200522
Abstract: The transformation of functional proteins into amyloidic plaques is responsible for the impairment of neurological functions in patients fallen victim to debilitating neurological conditions like Alzheimer's, Parkinson's and Huntington's diseases. The nucleating role of amyloid… read more here.
Keywords: inhibition fibrillation; fibrillation; amyloid hybrid; hybrid vesicles ... See more keywords
Hybrid lipid polymer nanoparticles for combined chemo- and photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00797
Abstract: Retinoblastoma is a malignant tumor of the retina in infants. Conventional therapies are associated to severe side effects and some of them induce secondary tumors. Photodynamic therapy (PDT) thus appears as a promising alternative as… read more here.
Keywords: hybrid lipid; photodynamic therapy; microscopy; combined chemo ... See more keywords
Partitioning of a Hybrid Lipid in Domains of Saturated and Unsaturated Lipids in a Model Cellular Membrane
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c04835
Abstract: The cellular membranes are composed of hundreds of components such as lipids, proteins, and sterols that are chemically and physically distinct from each other. The lipid–lipid and lipid–protein interactions form domains in this membrane, which… read more here.
Keywords: membrane; partitioning hybrid; saturated unsaturated; unsaturated lipid ... See more keywords
Optimized fluorodendrimer-incorporated hybrid lipid-polymer nanoparticles for efficient siRNA delivery.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/c9bm01738k
Abstract: Six cationic lipidoid fluorodendrimers are synthesized to construct hybrid lipid-polymer nanoparticles for siRNA delivery. By screening the nanoplatforms including fluorodendrimers with different chemical structures, the optimized nanoparticle NPF13-5 mediates the most efficient silencing of prohibitin… read more here.
Keywords: polymer nanoparticles; hybrid lipid; sirna delivery; lipid polymer ... See more keywords
Hybrid Lipid Nanoformulations for Hepatoma Therapy: Sorafenib Loaded Nanoliposomes—A Preliminary Study
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12162833
Abstract: Sorafenib is a multikinase inhibitor that has received increasing attention due to its high efficacy in hepatocellular carcinoma treatment. However, its poor pharmacokinetic properties (limited water solubility, rapid elimination, and metabolism) still represent major bottlenecks… read more here.
Keywords: nanoformulations hepatoma; sorafenib loaded; loaded nanoliposomes; hybrid lipid ... See more keywords
Effects of Hybrid Lipid Concentration on Equilibrium Domain Size in a Lipid Bilayer Immersed in Water
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Korean Physical Society"
DOI: 10.3938/jkps.73.1899
Abstract: The effects of introducing hybrid lipids to a lipid bilayer containing saturated and unsaturated lipids immersed in water were studied. The lipid and water molecules were modeled as coarse-grained particles. All particles were simulated by… read more here.
Keywords: hybrid lipid; immersed water; water; lipid concentration ... See more keywords