Synthesis and evaluation of cationic polymeric micelles as carriers of lumbrokinase for targeted thrombolysis
Sign Up to like & getrecommendations! Published in 2019 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2018.03.004
Abstract: To achieve targeted thrombolysis, a targeted delivery system of lumbrokinase (LK) was constructed using RGDfk-conjugated hybrid micelles. Based on the specific affinity of RGDfk to glycoprotein complex of GPⅡb/Ⅲa expressed on the surface of membrane… read more here.
Keywords: hybrid micelles; targeted thrombolysis; rgdfk conjugated; rgdfk ... See more keywords
Synthesis and Pickering emulsifier performance of Ag/poly((2-dimethylamino)ethyl methacrylate)-co-poly(hexafluorobutyl acrylate) amphiphilic random copolymer hybrid micelles
Sign Up to like & getrecommendations! Published in 2019 at "Reactive and Functional Polymers"
DOI: 10.1016/j.reactfunctpolym.2019.01.017
Abstract: Abstract A new type of comolymer containing nanoparticles, Ag/poly(2-(dimethylamino) ethyl methacrylate-co-hexafluorobutyl acrylate) (Ag/P(DMAEMA-co-HFBA)) amphiphilic random copolymer hybrid micelles was synthesized and used as the high-efficiency particulate emulsifiers to stabilize Pickering emulsion. Firstly, the amphilphilic random… read more here.
Keywords: hybrid micelles; dmaema hfba; copolymer; poly ... See more keywords
Tuning the Endocytosis of Hybrid Micelles through Spatial Regulation of Cationic Groups.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20620
Abstract: The ability of nanocarriers to enter tumor cells can be enhanced by positive surface charge. Nonetheless, the relationship between the spatial distributions of cationic groups and the endocytosis and tumor penetration of nanocarriers remains largely… read more here.
Keywords: cationic groups; tuning endocytosis; endocytosis hybrid; hybrid micelles ... See more keywords
Hybrid micelles enhance tumour therapy by remodelling biodistribution and improving intracellular drug release.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials science"
DOI: 10.1039/d1bm01158h
Abstract: PEGylated micelles have been widely used for tumour therapy. Although PEGylation can prolong the blood circulation time, there is only less than 5% of administered micelles that can be transported to tumour sites and over… read more here.
Keywords: hybrid micelles; drug release; intracellular drug; tumour therapy ... See more keywords