Cholinergic Neuron Targeting Nanosystem Delivering Hybrid Peptide for Combinatorial Mitochondrial Therapy in Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c05795
Abstract: Mitochondrial dysfunction in neurons has recently become a promising therapeutic target for Alzheimer's disease (AD). Regulation of dysfunctional mitochondria through multiple pathways rather than antioxidation monotherapy indicates synergistic therapeutic effects. Therefore, we developed a multifunctional… read more here.
Keywords: cholinergic neuron; alzheimer disease; hybrid peptide; peptide ... See more keywords
α,ε-Hybrid Peptide-Stabilized Magnetic Nanoparticle-Coated Paper-Based Actuators
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c08092
Abstract: The development of α,ε-hybrid peptide-stabilized magnetic nanoparticles and their application to fabricate a paper-based actuator has been reported. From single-crystal diffraction analysis, the nitropeptide 2 has an extended structure with a trans geometry. The one-pot… read more here.
Keywords: magnetic nanoparticle; paper based; peptide stabilized; stabilized magnetic ... See more keywords
The Antimicrobial Effect Against Multi-Drug Resistant Bacteria of The SK4 Peptide: a Novel Hybrid Peptide of Cecropin-A and BMAP-27.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1566524023666221031144028
Abstract: BACKGROUND Antibiotic-resistant is considered one of the critical health challenges in the management of infectious diseases. Resistant bacterial strains to the different types of antibacterial agents have been spread worldwide. Anti-microbial peptides (AMPs), also called… read more here.
Keywords: sk4 peptide; multi drug; activity; drug resistant ... See more keywords
In vitro Impact of Yeast Expressed Hybrid Peptide CATH-2TP5 as a Prophylactic Measure Toward Sepsis and Inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00454
Abstract: CATH-2TP5 is a linear cationic hybrid peptide, consequent from naturally occurring antimicrobial peptide (AMPs) Cathelicidin-2 (CATH-2) and Immunomodulatory peptide Thymopentin (TP5) having dynamic and potent anti-inflammatory activities without hemolytic effect. The biocompatible mechanism of CATH-2TP5… read more here.
Keywords: peptide cath; cath 2tp5; vitro impact; cath ... See more keywords
Expression of Hybrid Peptide EF-1 in Pichia pastoris, Its Purification, and Antimicrobial Characterization
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25235538
Abstract: EF-1 is a novel peptide derived from two bacteriocins, plantaricin E and plantaricin F. It has a strong antibacterial activity against Escherichia coli and with negligible hemolytic effect on red blood cells. However, the chemical… read more here.
Keywords: expression; hybrid peptide; pichia pastoris;