Design and Synthesis of Aminopyrimidinyl Pyrazole Analogs as PLK1 Inhibitors Using Hybrid 3D-QSAR and Molecular Docking
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DOI: 10.3390/ph15101170
Abstract: Cancer continues to be one of the world’s most severe public health issues. Polo-like kinase 1 (PLK1) is one of the most studied members of the polo-like kinase subfamily of serine/threonine protein kinases. PLK1 is… read more here.
Keywords: molecular docking; design synthesis; plk1; plk1 inhibitors ... See more keywords