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Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00608
Abstract: The identification and characterization of novel triazolopyridine derivatives with selective α5 subunit-containing GABAA receptor negative allosteric modulator (NAM) activity are disclosed. As a result of in silico screening of our corporate compound deck, we identified…
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Keywords:
hybridization approach;
gabaa receptor;
receptor negative;
identification ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27185923
Abstract: We synthesized a set of small molecules using a molecular hybridization approach with good yields. The antiviral properties of the synthesized conjugates against the SAR-CoV-2 virus were investigated and their cytotoxicity was also determined. Among…
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Keywords:
using molecular;
molecular hybridization;
hybridization approach;
sars cov ... See more keywords