Articles with "hybridization assay" as a keyword



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Epidemiology of Babesia, Anaplasma and Trypanosoma species using a new expanded reverse line blot hybridization assay.

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Published in 2018 at "Ticks and tick-borne diseases"

DOI: 10.1016/j.ttbdis.2017.08.011

Abstract: Vector-borne hemoparasitic infections are a major problem that affects livestock industries worldwide, particularly in tropical and subtropical regions. In this work, a reverse line blot (RLB) hybridization assay was developed for the simultaneous detection and… read more here.

Keywords: hybridization assay; epidemiology; anaplasma; reverse line ... See more keywords
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Conditional Displacement Hybridization Assay for Multiple SNP Phasing.

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Published in 2017 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.7b02300

Abstract: The two chromosomal copies of the human genome are highly polymorphic, and the allelic content on each strand can dictate a person's biological outcomes. While many of the current diagnostic tools are able to detect… read more here.

Keywords: conditional displacement; hybridization; hybridization assay; snp ... See more keywords
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Rapid identification and phylogenetic classification of diverse bacterial pathogens in a multiplexed hybridization assay targeting ribosomal RNA

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-40792-3

Abstract: Rapid bacterial identification remains a critical challenge in infectious disease diagnostics. We developed a novel molecular approach to detect and identify a wide diversity of bacterial pathogens in a single, simple assay, exploiting the conservation,… read more here.

Keywords: identification; hybridization assay; ribosomal rna; bacterial pathogens ... See more keywords
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Validation of a DKK1 RNAscope chromogenic in situ hybridization assay for gastric and gastroesophageal junction adenocarcinoma tumors

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-89060-3

Abstract: Dickkopf-1 (DKK1) is a secreted modulator of Wnt signaling that is frequently overexpressed in tumors and associated with poor clinical outcomes. DKN-01 is a humanized monoclonal therapeutic antibody that binds DKK1 with high affinity and… read more here.

Keywords: rnascope chromogenic; hybridization assay; dkk1 rnascope; rnascope ... See more keywords
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Novel In Situ Hybridization Assay for Chromogenic Single-Molecule Detection of Human Papillomavirus E6/E7 mRNA

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Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.03896-22

Abstract: In situ detection of viral mRNA expression in tissue samples is of great value for pathological diagnosis to access viral infection status. Unfortunately, conventional RNA in situ hybridization assays lack sensitivity and specificity for clinical… read more here.

Keywords: situ hybridization; mrna; hybridization; hybridization assay ... See more keywords
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Sandwich Hybridization Assay for In Situ Real-Time Cyanobacterial Detection and Monitoring: A Review

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Published in 2022 at "Biosensors"

DOI: 10.3390/bios12080640

Abstract: As cyanobacterial harmful algal bloom (cHAB) events increase in scale, severity, frequency, and duration around the world, rapid and accurate monitoring and characterization tools have become critically essential for regulatory and management decision-making. The composition… read more here.

Keywords: time; sandwich hybridization; detection; real time ... See more keywords