Design and Hybridization Properties of Acyclic Xeno Nucleic Acid Oligomers
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100184
Abstract: Xeno nucleic acids (XNAs) are analogues of DNA and RNA that have a non‐ribose artificial scaffold. XNAs are possible prebiotic genetic carriers as well as alternative genetic systems in artificial life. In addition, XNA oligomers… read more here.
Keywords: acyclic xeno; xeno nucleic; design hybridization; properties acyclic ... See more keywords
Synthesis and hybridization properties of oligonucleotide analogues with novel acyclic triazole internucleotide linkages.
Sign Up to like & getrecommendations! Published in 2017 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2017.04.004
Abstract: Herein, we describe synthesis of novel acyclic dinucleotide analogues connected via triazole linkage in CuAAC reaction. Synthesis pathway starting from previously obtained building blocks containing alkyne or azide functional group is described. Further functionalization and… read more here.
Keywords: novel acyclic; oligonucleotide analogues; properties oligonucleotide; hybridization properties ... See more keywords