Design and Synthesis of 2,5-Disubstituted-1,3,4-Oxadiazole Hybrids Bearing Pyridine and 1,2,3-Triazole Pharmacophores
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DOI: 10.1002/jhet.2672
Abstract: A novel series of 2,5-disubstituted-1,3,4-oxadiazoles decorated with two biodynamic moieties pyridine and 1,2,3-triazole have been successfully synthesized in good yields under mild reaction conditions. The synthesized compounds are valuable for biological activity exploration since three… read more here.
Keywords: design synthesis; hybrids bearing; pyridine triazole; disubstituted oxadiazole ... See more keywords
Design, synthetic approach, in silico molecular docking and antibacterial activity of quinazolin-2,4-dione hybrids bearing bioactive scaffolds
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DOI: 10.1039/d2ra06527d
Abstract: Antimicrobial resistance (AMR) is one of ten global public health threats facing humanity. This created the need to identify and develop effective inhibitors as antimicrobial agents. In this respect, quinazolin-2,4-dione hybrids bearing N-heterocyclic cores such… read more here.
Keywords: quinazolin dione; dione hybrids; dione; hybrids bearing ... See more keywords