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Published in 2021 at "Frontiers in Chemistry"
DOI: 10.26083/tuprints-00019433
Abstract: Herein, we present the design, synthesis, and biological evaluation of novel integrin-targeting molecular hybrids combining RGD peptides and a potent cytotoxin presented on dextran polysaccharides. Based on an aglycosylated Fc as a centerpiece, endosomal-cleavable cytotoxic…
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Keywords:
synthetic integrin;
integrin;
hybrids efficiently;
dextran hybrids ... See more keywords