The immune microenvironment of the hydatidiform mole.
Sign Up to like & getrecommendations! Published in 2021 at "Human pathology"
DOI: 10.1016/j.humpath.2021.12.002
Abstract: BACKGROUND Gestational trophoblastic diseases (GTD) are a heterogeneous group of lesions, the most frequent being the hydatidiform mole (HM). HM are usually cured after surgical treatment or after chemotherapy in the case of a persistent… read more here.
Keywords: hydatidiform mole; microenvironment; microenvironment hydatidiform; immune microenvironment ... See more keywords
Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia
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DOI: 10.1038/s41598-019-46660-4
Abstract: Hydatidiform moles are known to pose an extremely high risk of severe early-onset preeclampsia if left untreated. TNF superfamily cytokine, LIGHT has recently been reported to contribute to pathophysiology of preeclampsia. The present study aimed… read more here.
Keywords: hydatidiform mole; preeclampsia; increased light; trophoblast cells ... See more keywords
Dietary Factors and Incidence of Hydatidiform Mole: An Ecological Study
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DOI: 10.1080/01635581.2022.2079688
Abstract: Abstract The current ecological study aims to explore the association between dietary factors and hydatidiform mole (HM) incidence in Japan and China. HM incidence in Japan gradually declined from 1970s to 1990s, while the dietary… read more here.
Keywords: dietary factors; proportion; incidence; hydatidiform mole ... See more keywords
Misdiagnosis of placental mesenchymal dysplasia as pregnancy with hydatidiform mole: A case report and literature review
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DOI: 10.1097/md.0000000000033438
Abstract: Rationale: Placental mesenchymal dysplasia (PMD) is a rare placental disease frequently associated with severe maternal and/or fetal complications. Its sonographic appearance is very similar to that of a hydatidiform mole. Hence, PMD is easily misdiagnosed… read more here.
Keywords: hydatidiform; hydatidiform mole; placental mesenchymal; pregnancy hydatidiform ... See more keywords
Centralized surveillance of hydatidiform mole: 7-year experience from a regional hospital in China
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-002797
Abstract: Objective To assess the strategy and value of centralized surveillance of hydatidiform mole at a regional hospital in China and to investigate the necessity of prophylactic chemotherapy for high-risk complete hydatidiform mole. Methods Between February… read more here.
Keywords: risk; trophoblastic neoplasia; surveillance; hydatidiform ... See more keywords
Comparison of different therapeutic strategies for complete hydatidiform mole in women at least 40 years old: a retrospective cohort study
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DOI: 10.1186/s12885-017-3749-8
Abstract: BackgroundThere are three main therapeutic strategies, namely expectant management (dilation and curettage only), prophylactic chemotherapy and prophylactic total hysterectomy for treating older women with complete hydatidiform mole (CHM). However, the scientific community has so far,… read more here.
Keywords: years old; group; least years; therapeutic strategies ... See more keywords
Expression of Pro-Apoptotic Bax and Anti-Apoptotic Bcl-2 Proteins in Hydatidiform Moles and Placentas With Hydropic Changes
Sign Up to like & getrecommendations! Published in 2019 at "ACTA MEDICA IRANICA"
DOI: 10.18502/acta.v57i1.1750
Abstract: Abstract- Morphologic examination still forms the main diagnostic tool in the differential diagnosis of molar placentas. However the criteria are subjective and show considerable inter-observer variability among pathologists. The aim of the present study was… read more here.
Keywords: partial hydatidiform; hydropic; complete hydatidiform; hydatidiform ... See more keywords
Whole-exome sequencing reveals genetic variants in ERC1 and KCNG4 associated with complete hydatidiform mole in Chinese Han women
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20769
Abstract: Complete hydatidiform mole (CHM) is a rare pregnancy-related disease with invasive potential. The genetics underlying the sporadic form of CHM have not been addressed previously, but maternal genetic variants may be involved in biparental CHM.… read more here.
Keywords: exome sequencing; genetic variants; hydatidiform mole; complete hydatidiform ... See more keywords