The radical SAM enzyme HydE generates adenosylated Fe(I) intermediates en route to the [FeFe]-hydrogenase catalytic H-cluster.
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DOI: 10.1021/jacs.0c03802
Abstract: The H-cluster of [FeFe]-hydrogenase consists of a [4Fe-4S]H-subcluster linked by a cysteinyl bridge to a unique organometallic [2Fe]H-subcluster assigned as the site of interconversion between protons and molecular hydrogen. This [2Fe]H-subcluster is assembled by a… read more here.
Keywords: radical sam; fefe hydrogenase; sam enzyme; hyde ... See more keywords
Crystal Structure of the [FeFe]-Hydrogenase Maturase HydE Bound to Complex-B.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c03367
Abstract: [FeFe]-hydrogenases use a unique organometallic complex, termed the H cluster, to reversibly convert H2 into protons and low-potential electrons. It can be best described as a [Fe4S4] cluster coupled to a unique [2Fe]H center where… read more here.
Keywords: crystal structure; bound; 2fe center; crystal ... See more keywords