Articles with "hydralazine" as a keyword



Cardioprotection of hydralazine against myocardial ischemia/reperfusion injury in rats.

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Published in 2019 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2019.172850

Abstract: This study aimed to investigate whether hydralazine could reduce cardiac ischemia/reperfusion (I/R) injury in rats. Anesthetized male Sprague-Dawley rats underwent myocardial I/R injury. Saline, hydralazine (HYD, 10-30 mg/kg) was administered intraperitoneally 10 min before reperfusion. After 30 min… read more here.

Keywords: reperfusion; hydralazine; ischemia reperfusion; reperfusion injury ... See more keywords
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A hydralazine-induced triumvirate: Lupus, cutaneous vasculitis, and cryptococcoid Sweet syndrome

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Published in 2019 at "JAAD Case Reports"

DOI: 10.1016/j.jdcr.2019.08.020

Abstract: Hydralazine is a commonly prescribed antihypertensive medication that has been associated with both drug-induced lupus erythematosus and vasculitis.1 There is significant clinical, histopathologic, and serologic overlap between these entities. We present an unusual case of… read more here.

Keywords: sweet syndrome; vasculitis; induced triumvirate; hydralazine ... See more keywords
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Hydralazine-induced pericardial effusion

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Published in 2019 at "Baylor University Medical Center Proceedings"

DOI: 10.1080/08998280.2019.1613331

Abstract: Abstract Drug-induced lupus (DIL) is due to an autoimmune reaction to a drug with an estimated incidence of 15,000 to 30,000 cases every year in the US. Hydralazine is a well-known offender. Antinuclear antibody (ANA)… read more here.

Keywords: dil; induced pericardial; hydralazine; hydralazine induced ... See more keywords
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Hydralazine protects the heart against acute ischemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission.

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Published in 2021 at "Cardiovascular research"

DOI: 10.1093/cvr/cvaa343

Abstract: AIMS Genetic and pharmacological inhibition of mitochondrial fission induced by acute myocardial ischaemia/reperfusion injury has been shown to reduce myocardial infarct size. The clinically used anti-hypertensive and heart failure medication, hydralazine, is known to have… read more here.

Keywords: hydralazine; reperfusion injury; heart; mitochondrial fission ... See more keywords