Automated fluorimetric determination of the genotoxic impurity hydrazine in allopurinol pharmaceuticals using zone fluidics and on-line solid phase extraction.
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DOI: 10.1016/j.jpba.2019.112887
Abstract: In the present study we report a fully automated method for the determination of low levels of the genotoxic impurity hydrazine in allopurinol active pharmaceutical ingredient (API) and formulations based on the concept of zone-fluidics.… read more here.
Keywords: line; line solid; zone fluidics; genotoxic impurity ... See more keywords