Similarity-Based Profiling of Hydrazone-Containing Scaffolds Active Against Leishmania Amastigotes
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DOI: 10.1021/acsomega.5c05276
Abstract: This review explores the potential of hydrazone-containing scaffolds as anti-leishmanial agents with a particular focus on their activity against intracellular Leishmania amastigotes. Through a strategy centered on the 3D electroshape properties of compounds, structural analysis… read more here.
Keywords: leishmania amastigotes; hydrazone containing; hydrazone; similarity based ... See more keywords
Multistage Reversible Tg Photomodulation and Hardening of Hydrazone-Containing Polymers.
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DOI: 10.1021/jacs.1c07504
Abstract: The glass transition temperature (Tg) of a series of polyacrylate- and polymethacrylate-based polymers having bistable hydrazone photoswitches as pendants increases upon photoisomerization. The ensuing photohardening of the polymeric network was corroborated using nanoindentation measurements. The… read more here.
Keywords: reversible photomodulation; photomodulation hardening; hydrazone containing; hardening hydrazone ... See more keywords
Acid-labile poly(ethylene glycol) shell of hydrazone-containing biodegradable polymeric micelles facilitating anticancer drug delivery
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bioactive and Compatible Polymers"
DOI: 10.1177/0883911517715658
Abstract: Biodegradable pH-sensitive amphiphilic block polymer (mPEG-Hyde-PLGA) was synthesized via ring-opening polymerization, initiated from a hydrazone-containing macro-initiator. In this way, a pH-sensitive hydrazone bond was inserted into the backbone of block copolymer, linking hydrophilic poly(ethylene glycol)… read more here.
Keywords: drug delivery; drug; hydrazone containing; poly ethylene ... See more keywords