(η5‐Pentamethylcyclopentadienyl)iridium Complex Catalyzed Imine Reductions Utilizing the Biomimetic 1,4‐NAD(P)H Cofactor and N‐Benzyl‐1,4‐dihydronicotinamide as the Hydride‐Transfer Agent
Sign Up to like & getrecommendations! Published in 2017 at "ChemCatChem"
DOI: 10.1002/cctc.201601307
Abstract: The interaction between synthetic organometallic complexes and metabolic cofactors has proven to be a newly emerging topic in bioorganometallic chemistry. Thus, the first cationic Cp*Ir‐catalyzed (Cp*=η5‐pentamethylcyclopentadienyl) imine reduction in neutral buffered aqueous medium was examined.… read more here.
Keywords: hydride; iridium complex; imine; hydride transfer ... See more keywords
Photoinduced Catalytic Organic-Hydride Transfer to CO2 Mediated with Ruthenium Complexes as NAD+/NADH Redox Couple Models.
Sign Up to like & getrecommendations! Published in 2023 at "ChemSusChem"
DOI: 10.1002/cssc.202300032
Abstract: The catalytic organic-hydride transfer to CO2 was first achieved through the photoinduced two-electron reduction of the [Ru(bpy)2(pbn)]2+/[Ru(bpy)2(pbnHH)]2+ (bpy = 2,2'-bipyridine, pbn = 2-(pyridin-2-yl)benzo[b]-1,5-naphthyridine, and pbnHH = 2-(pyridin-2-yl)-5,10-dihydrobenzo[b]-1,5-naphthyridine) redox couple in the presence of 1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzo[d]imidazole (BIH).… read more here.
Keywords: hydride transfer; bpy; catalytic organic; organic hydride ... See more keywords
Organometallic hydride-transfer agents as reductants for organic semiconductor molecules
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2019.02.003
Abstract: Abstract Both organic hydride donors, DH, and the dimers formed by some organic radicals and by some 19-electron organometallic sandwich compounds, D2, have recently been examined extensively as n-dopants for organic semiconductors. This properties of… read more here.
Keywords: hydride transfer; electrochemistry; reductants organic; agents reductants ... See more keywords
A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.08.028
Abstract: Metabolic rewiring and redox balance play pivotal roles in cancer. Cellular senescence is a barrier for tumorigenesis circumvented in cancer cells by poorly understood mechanisms. We report a multi-enzymatic complex that reprograms NAD metabolism by… read more here.
Keywords: nad metabolism; complex reprograms; senescence; hydride transfer ... See more keywords
Iron-catalyzed chemoselective hydride transfer reactions
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132187
Abstract: ABSTRACT A Diaminocyclopentadienone iron tricarbonyl complex has been applied in chemoselective hydrogen transfer reductions. This bifunctional iron complex demonstrated a broad applicability in mild conditions in various reactions, such as reduction of aldehydes over ketones,… read more here.
Keywords: iron catalyzed; catalyzed chemoselective; chemoselective hydride; hydride transfer ... See more keywords
Designing Catalytic Systems Using Binary Solvent Mixtures: Impact of Mole Fraction of Water on Hydride Transfer.
Sign Up to like & getrecommendations! Published in 2021 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.1c02397
Abstract: The free energy for hydride transfer reactions of transition metal hydrides is known to be influenced by solvent effects. The first-row transition metal hydride [HNi(dmpe)2][BF4] (dmpe = 1,2-bis(dimethylphosphino)ethane) has starkly different hydride transfer reactivities with… read more here.
Keywords: fraction water; hydride; mole fraction; hydride transfer ... See more keywords
Exploration of Ligand-Centered Hydride Transfer in La/Y-Catalyzed Deoxygenative Reduction of Tertiary Amides with Pinacolborane.
Sign Up to like & getrecommendations! Published in 2023 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c03793
Abstract: A number of rare-earth metals and actinides have proven to be active in a wide variety of atom-efficient transformations. As compared to the related organometallic catalysts, the detailed mechanisms for the rare-earth metal-catalyzed reactions remain… read more here.
Keywords: hydride transfer; deoxygenative reduction; amides pinacolborane; transfer ... See more keywords
Reversible Hydride Transfer to N,N'-Diarylimidazolinium Cations from Hydrogen Catalyzed by Transition Metal Complexes Mimicking the Reaction of [Fe]-Hydrogenase.
Sign Up to like & getrecommendations! Published in 2017 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.7b00806
Abstract: [Fe]-hydrogenase is a key enzyme involved in methanogenesis and facilitates reversible hydride transfer from H2 to N5,N10-methenyltetrahydromethanopterin (CH-H4MPT+). In this study, a reaction system was developed to model the enzymatic function of [Fe]-hydrogenase by using… read more here.
Keywords: hydride; hydride transfer; hydrogenase; reaction ... See more keywords
Hydride Transfer-Initiated Cross-Dehydrogenative Coupling Reaction to Access Nine-Membered Rings.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00193
Abstract: An unprecedented hydride transfer-triggered cross-dehydrogenative coupling of two C(sp3)-H bonds to target nine-membered rings has been developed. Salient features of this methodology include atom and step economy and metal-free and redox-neutral conditions, with water as… read more here.
Keywords: nine membered; membered rings; hydride transfer; dehydrogenative coupling ... See more keywords
Organocatalytic Cascade β-Functionalization/Aromatization of Pyrrolidines via Double Hydride Transfer.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03918
Abstract: An unprecedented cascade β-functionalization/aromatization reaction of N-arylpyrrolidines was established. A series of β-substituted arylpyrroles embedded with trifluoromethyl groups are provided directly from N-arylpyrrolidines. The deuterium-labeling experiments indicate that sequential double hydride transfer processes serve as… read more here.
Keywords: double hydride; hydride transfer; functionalization aromatization; cascade functionalization ... See more keywords
Hydride Transfer Mechanism of Enzymatic Sugar Nucleotide C2 Epimerization Probed with a Loose-Fit CDP-Glucose Substrate
Sign Up to like & getrecommendations! Published in 2022 at "ACS Catalysis"
DOI: 10.1021/acscatal.2c00257
Abstract: Transient oxidation–reduction through hydride transfer with tightly bound NAD coenzyme is used by a large class of sugar nucleotide epimerases to promote configurational inversion of carbon stereocenters in carbohydrate substrates. A requirement for the epimerases… read more here.
Keywords: hydride transfer; hydride; substrate; cdp glucose ... See more keywords