Exogenous Ligand-Free NiH-Catalyzed Hydroacylation of Aryl Alkenes with Aroyl Fluorides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02110
Abstract: Acyl fluorides have emerged as efficient acyl group donors, but these attractive reagents have rarely been utilized in transition-metal-catalyzed hydroacylation. Herein we report a nickel hydride-catalyzed hydroacylation of aryl alkenes using aroyl fluorides. The reaction… read more here.
Keywords: hydroacylation; aroyl fluorides; hydroacylation aryl; catalyzed hydroacylation ... See more keywords
Photoredox-Ni Dual Catalysis: Chelation-Free Hydroacylation of Terminal Alkynes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03481
Abstract: Hydroacylation of alkynes is undoubtedly the simplest and most atom-efficient approach for the synthesis of enones with diverse synthetic applications. Despite significant progress in hydroacylations, no hydroacylations exist that make use of aldehydes without a… read more here.
Keywords: hydroacylation; catalysis chelation; dual catalysis; terminal alkynes ... See more keywords
Azine-N-oxides as effective controlling groups for Rh-catalysed intermolecular alkyne hydroacylation
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DOI: 10.1039/d1sc03915f
Abstract: Heterocycle-derived aldehydes are challenging substrates in metal-catalysed hydroacylation chemistry. We show that by using azine N-oxide substituted aldehydes, good reactivity can be achieved, and that they are highly effective substrates for the intermolecular hydroacylation of… read more here.
Keywords: oxides effective; effective controlling; azine; controlling groups ... See more keywords
Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade
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DOI: 10.1039/d1sc06900d
Abstract: Rhodium-catalyzed hydroacylation using alkynes substituted with pendant nucleophiles, delivers linear α,β-unsaturated enone intermediates with excellent regioselectivity. These adducts are used to construct a broad range of diversely substituted, saturated O-, N- and S-heterocycles in a… read more here.
Keywords: hydroacylation conjugate; conjugate addition; saturated heterocycles; heterocycles hydroacylation ... See more keywords
Visible-light-induced energy-transfer-mediated hydroacylation of alkenes with alcohol-derived oximes.
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DOI: 10.1039/d5cc03772g
Abstract: Herein, we report a visible light-driven hydroacylation strategy for the efficient synthesis of 1,4-ketoesters from alkenes and alcohol-derived oximes under mild conditions. The reaction proceeds via an energy transfer (EnT)-mediated pathway, wherein homolytic N-O bond… read more here.
Keywords: derived oximes; alcohol derived; visible light; alkenes alcohol ... See more keywords
Photo- and Cu(I)-Promoted Branched-Selective Formal Hydroacylation of Terminal Alkynes via the Intermolecular Coupling of Siloxycarbenes with Alkyne–Cu Complexes
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DOI: 10.1093/chemle/upaf084
Abstract: A photoinduced and copper-promoted coupling reaction of alkanoylsilanes and terminal acetylenes, which affords the corresponding α, β-enones in branched-selective manner, the formal hydroacylation products, has been developed. The established coupling is expected to proceed via… read more here.
Keywords: photo promoted; hydroacylation; formal hydroacylation; selective formal ... See more keywords
Lewis Acid-assisted Dirhodium(II)-catalyzed Ketone Hydroacylation
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DOI: 10.1246/cl.160862
Abstract: The combination of a Rh(II) salt and a Lewis acid, Sc(OTf)3, as a highly active and robust cooperative catalyst system for ketone hydroacylation was developed. The catalyst system showed high turnover numbers (up to ca.… read more here.
Keywords: lewis acid; system; ketone hydroacylation; assisted dirhodium ... See more keywords
Mechanistic Insight Into the AuCN Catalyzed Annulation Reaction of Salicylaldehyde and Aryl Acetylene: Cyanide Ion Promoted Umpolung Hydroacylation/Intramolecular Oxa-Michael Addition Mechanism
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2019.00557
Abstract: The detailed mechanism of the AuCN-catalyzed annulation of salicylaldehyde (SA) and phenyl acetylene leading to isoflavanone-type complexes has been investigated via density functional theory (DFT) calculations. Reaction pathways and possible stationary points are obtained with… read more here.
Keywords: mechanism; aucn catalyzed; cyanide ion; ion ... See more keywords