Deciphering the mechanism of the nickel-catalyzed hydroalkoxylation reaction: A combined experimental and computational study
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DOI: 10.1021/acscatal.7b00616
Abstract: ABSTRACT: The [Ni(COD)2]/P P-catalysed hydroalkoxylation of butadiene to form butenyl ethers is studied mechanistically, where P P = 1,4-bis(diphenylphosphino)butane (dppb) and 1,2-bis(diphenylphosphinomethyl)benzene (dppmb). Experimental studies suggest the intermediacy of [(P P)Ni(0)(butadiene)] and [(P P)Ni(II)(allyl)] intermediates… read more here.
Keywords: hydroalkoxylation; deciphering mechanism; hydroalkoxylation reaction; nickel catalyzed ... See more keywords
Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b01089
Abstract: Hydroalkoxylation is a powerful and efficient method of forming C-O bonds and cyclic ethers in synthetic chemistry. In studying the biosynthesis of the fungal natural product herqueinone, we identified an enzyme that can perform an… read more here.
Keywords: hydroalkoxylation; enantioselective hydroalkoxylation; reaction; enzyme catalyzed ... See more keywords