Catalytic and metal-free intramolecular hydroalkoxylation of alkynes
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.01.020
Abstract: Abstract Benzyltrimethylammonium hydroxide act as an efficient metal-free catalyst for the intramolecular hydroalkoxylation of alkynes. Notably, the use of microwave irradiation allowed reaction to operate in only two minutes. Under optimized reaction conditions, linear alkynes… read more here.
Keywords: catalytic metal; intramolecular hydroalkoxylation; hydroalkoxylation alkynes; metal free ... See more keywords
Gold(I)-Catalyzed Intramolecular Hydroamination and Hydroalkoxylation of Alkynes: Access to Original Heterospirocycles.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02070
Abstract: We report here a simple and robust gold-catalyzed annulation reaction, giving N- and O-spirocycles in good to excellent yields. We have prepared a library of protected amines and tertiary alcohols that give, upon cyclization with… read more here.
Keywords: hydroamination hydroalkoxylation; alkynes access; gold catalyzed; hydroalkoxylation alkynes ... See more keywords