A multi-function hydrogel-coating engineered implant for rescuing biofilm infection and boosting osseointegration by macrophage-related immunomodulation.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300722
Abstract: Incurable bacterial infections, impenetrable microbial biofilm and dysregulated immune microenvironments are among the most intractable threats for the treatment of implant-associated infections (IAIs). Innovative methodologies combined with reactive oxygen species (ROS) scavenging suppress the oxidative… read more here.
Keywords: biofilm; macrophage; hydrogel coating; infection ... See more keywords
Mechanical‐Enhanced and Durable Zwitterionic Hydrogel Coating for Inhibiting Coagulation and Reducing Bacterial Infection
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202400126
Abstract: Blood‐contact medical devices are indispensable for clinical interventions, yet their susceptibility to thrombosis and bacterial infections poses substantial risks to treatment efficacy and patient well‐being. This study introduces a polysulfobetaine/alginate‐CuII (SAC) zwitterionic hydrogel coating on… read more here.
Keywords: zwitterionic hydrogel; hydrogel; blood; mechanical enhanced ... See more keywords
Mucosa‐Like Conformal Hydrogel Coating for Aqueous Lubrication
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202108848
Abstract: Mucosa is a protective and lubricating barrier in biological tissue, which has a great clinical inspiration because of its slippery, soft, and hydrophilic surface. However, mimicking mucosal traits on complex surface remains an enormous challenge.… read more here.
Keywords: mucosa like; hydrogel coating; conformal hydrogel; hydrogel ... See more keywords
One‐Pot Construction of Articular Cartilage‐Like Hydrogel Coating for Durable Aqueous Lubrication
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202309141
Abstract: Articular cartilage has an appropriate multilayer structure and superior tribological properties and provides a structural paradigm for design of lubricating materials. However, mimicking articular cartilage traits on prosthetic materials with durable lubrication remains a huge… read more here.
Keywords: cartilage like; hydrogel; articular cartilage; lubrication ... See more keywords
Adhesive Gelatin/Chitosan Hydrogel Coating Containing MgO Nanoparticles for Promoting Soft Tissue Integration.
Sign Up to like & getrecommendations! Published in 2025 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202500231
Abstract: The implant‐soft tissue interface is critical for successful integration. However, developing multifunctional coatings that combine antibacterial action, strong interfacial adhesion, and regenerative capacity remains a significant challenge. This study presents a novel hydrogel coating for… read more here.
Keywords: integration; gelatin chitosan; tissue; hydrogel coating ... See more keywords
Preparation of vancomycin-loaded alginate hydrogel coating on magnesium alloy with enhanced anticorrosion and antibacterial properties
Sign Up to like & getrecommendations! Published in 2020 at "Thin Solid Films"
DOI: 10.1016/j.tsf.2019.137679
Abstract: Abstract In this study, vancomycin (Van)-loaded sodium alginate (SA) hydrogel coating was fabricated on micro-arc oxidation (MAO)-treated magnesium alloy (MgA) surface via the electrostatic interaction between polyethyleneimine and SA to enhance anticorrosion, hemocompatibility, and antibacterial… read more here.
Keywords: hydrogel; anticorrosion; mga; hydrogel coating ... See more keywords
Hemocompatibility Multi-in-One Hydrogel Coating with ROS-Triggered Inflammation Suppression and Anti-Infection Properties for Blood-Contacting Device.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00815
Abstract: In traditional blood-contacting medical devices, infection and thrombosis are easily formed on the surface of the materials. In addition, inflammation is also a clinical complication that cannot be ignored. More importantly, there is a mutually… read more here.
Keywords: hydrogel coating; blood contacting; infection; anti inflammatory ... See more keywords
Simultaneous and Efficient Removal of Oleophilic and Hydrophilic Stains from Polyurethane by the Combination of Easy-Cleaning and Self-Cleaning.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c01042
Abstract: The simultaneous and efficient removal of oleophilic and hydrophilic stains from polyurethane (PU) is realized by combining the easy-cleaning from the hydrophilic thermoresponsive hydrogel coating containing acrylamide (AAm), gum arabic (GA), and (ethylene glycol) methyl… read more here.
Keywords: easy cleaning; hydrogel coating; self cleaning; simultaneous efficient ... See more keywords
Biodegradable and Cytocompatible Hydrogel Coating with Antibacterial Activity for the Prevention of Implant-Associated Infection.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20401
Abstract: Implant-associated infection (IAI) caused by pathogens colonizing on the implant surface is a serious issue in the trauma-orthopedic surgery, which often leads to implant failure. The complications of IAI bring a big threat to the… read more here.
Keywords: implant associated; biodegradable cytocompatible; hydrogel coating; hydrogel ... See more keywords
Growth of Double-Network Tough Hydrogel Coatings by Surface-Initiated Polymerization.
Sign Up to like & getrecommendations! Published in 2024 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.4c00370
Abstract: Hydrogel coatings exhibit versatile applications in biomedicine, flexible electronics, and environmental science. However, current coating methods encounter challenges in simultaneously achieving strong interfacial bonding, robust hydrogel coatings, and the ability to coat substrates with controlled… read more here.
Keywords: tough hydrogel; hydrogel; network tough; hydrogel coatings ... See more keywords
Mucus Mimic Hydrogel Coating for Lubricous, Antibiofouling, and Anti-Inflammatory Urinary Catheters.
Sign Up to like & getrecommendations! Published in 2024 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.4c13051
Abstract: Silicone is a common elastomer used in indwelling urinary catheters, and catheters are widely used in various medical applications due to their exceptional biocompatibility, hypoallergenic properties, and flexibility. However, silicones exhibit hydrophobic characteristics, lack inherent… read more here.
Keywords: hydrogel; mimic hydrogel; urinary catheters; mucus mimic ... See more keywords