Ionic Liquid‐Mediated Delivery of Ruxolitinib to Skin Using an Adhesive Topical Hydrogel System
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202501838
Abstract: Delivery of many drug types to the skin is prohibited by the stratum corneum, and drugs that can penetrate the epidermal barrier (e.g., small, nonpolar molecules) often have limited permeation in the dermis. Ionic liquids… read more here.
Keywords: hydrogel system; hydrogel; delivery; drug ... See more keywords
Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202503338
Abstract: Advanced periodontitis initiates with Porphyromonas gingivalis (P. gingivalis) infection, which subsequently triggers chronic inflammation, immune imbalance, and ultimately causes alveolar bone resorption. Traditional periodontal treatment focuses on the elimination of triggering factors, but tend to… read more here.
Keywords: treatment; periodontitis; hydrogel system; hydrogel ... See more keywords
Injectable Hydrogel System Incorporating Black Phosphorus Nanosheets and Tazarotene Drug for Enhanced Vascular and Nerve Regeneration in Spinal Cord Injury Repair.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202310194
Abstract: Spinal cord injury (SCI) often leads to cell death, vascular disruption, axonal signal interruption, and permanent functional damage. Currently, there are no clearly effective therapeutic options available for SCI. Considering the inhospitable SCI milieu typified… read more here.
Keywords: hydrogel system; hydrogel; drug; injury ... See more keywords
Synthetic algal-bacteria consortia for space-efficient microalgal growth in a simple hydrogel system
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-021-02528-7
Abstract: Photosynthetic microalgae are an attractive source of food, fuel, or nutraceuticals, but commercial production of microalgae is limited by low spatial efficiency. In the present study we developed a simple photosynthetic hydrogel system that cultivates… read more here.
Keywords: growth; hydrogel; hydrogel system; space efficient ... See more keywords
Injectable polymeric nanoparticle hydrogel system for long-term anti-inflammatory effect to treat osteoarthritis
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.05.028
Abstract: Treatment of osteoarthritis (OA) by administration of corticosteroids is a commonly used method in clinics using anti-inflammatory medicine. Oral administration or intra-articular injection of corticosteroids can reduce the pain and progress of cartilage degeneration, but… read more here.
Keywords: anti inflammatory; long term; hydrogel system; term anti ... See more keywords
Synthesis of pH responsive, photocrosslinked gelatin-based hydrogel system for control release of ceftriaxone.
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2021.105101
Abstract: Stimuli-responsive or smart nanocarriers are emerging class of materials used for drug delivery and tissue engineering applications. The objective of this study was to develop environment friendly, economic and smart gelatin based hydrogel for controlled… read more here.
Keywords: based hydrogel; hydrogel system; drug; gelatin based ... See more keywords
Ultrahard and Ultraflexible Supramolecular Hydrogel with Superenergy Dissipating Structure for Biomimetic Skin.
Sign Up to like & getrecommendations! Published in 2024 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.4c17325
Abstract: How to integrate the "soft" (flexibility and self-healing properties) and "hard" (shape retention) into the supramolecular hydrogel system is an attractive challenge. In this work, a supramolecular hydrogel with an energy dissipation structure is designed… read more here.
Keywords: biomimetic skin; hydrogel system; hydrogel; structure ... See more keywords
A terpyridine based hydrogel system for reversible transmissive-to-dark electrochromism and bright-to-quenched electrofluorochromism.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02384a
Abstract: A carboxylic acid-containing terpyridine-based hydrogelator (TPPCA) is synthesized to afford a self-assembly induced TPPCA hydrogel, which was used as an all-in-one electrochrome in electrochromic devices (ECDs) to demonstrate reversible transparent-to-black electrochromism with fast darkening and… read more here.
Keywords: electrochromism; hydrogel; hydrogel system; terpyridine based ... See more keywords
MBRS-43. MODELLING MEDULLOBLASTOMA INVASION AND CHEMORESISTANCE IN A 3D HYALURONAN HYDROGEL SYSTEM
Sign Up to like & getrecommendations! Published in 2018 at "Neuro-oncology"
DOI: 10.1093/neuonc/noy059.488
Abstract: Medulloblastoma (MB) is the most common malignant paediatric brain tumour. High rates of metastasis and chemoresistance demand new, subgroup specific therapy approaches. The development of reliable and realistic model systems will allow us to investigate… read more here.
Keywords: chemoresistance; hydrogel system; invasion chemoresistance; model ... See more keywords
Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/9968602
Abstract: Background Chemotherapeutic drugs cause severe toxicities if administered unprotected, without proper targeting, and controlled release. In this study, we developed topotecan- (TPT-) loaded solid lipid nanoparticles (SLNs) for their chemotherapeutic effect against colorectal cancer. The… read more here.
Keywords: tpt slns; thermoresponsive hydrogel; hydrogel system; tpt ... See more keywords
Novel hydrogel system eliminates subculturing and improves retention of nonsenescent mesenchymal stem cell populations
Sign Up to like & getrecommendations! Published in 2022 at "Regenerative Medicine"
DOI: 10.2217/rme-2022-0140
Abstract: Aim To compare the physiological behavior of mesenchymal stem/stromal cells (MSCs) within an expandable tissue-mimetic 3D system relative to in vitro expansion in a traditional 2D system. Methods Adipose-derived MSCs (ASCs) were continuously cultured for… read more here.
Keywords: system; cell populations; hydrogel system; mesenchymal stem ... See more keywords