Gas-Phase Peptide Fragmentation Induced by Hydrogen Attachment, from Principle to Sequencing of Amide Nitrogen-Methylated Peptides.
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DOI: 10.1021/acs.analchem.0c02766
Abstract: Tandem mass spectrometry (MS/MS) with radical-based fragmentation was developed recently, which involves the reaction of hydrogen atoms and peptides in a process called hydrogen attachment/abstraction dissociation (HAD). HAD mainly produces [cn + 2H]+ and [zm… read more here.
Keywords: hydrogen; peptide backbone; hydrogen attachment; gas phase ... See more keywords