Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability
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DOI: 10.1126/scitranslmed.aam6474
Abstract: Tenapanor inhibits sodium/hydrogen exchanger isoform 3 to reduce intestinal phosphate absorption via reduction of passive paracellular phosphate flux. Phosphate in flux Kidney failure can decrease the excretion of phosphate, leading to elevated phosphate in the… read more here.
Keywords: hydrogen exchanger; sodium; sodium hydrogen; tenapanor ... See more keywords