Synthesis of chiral γ-lactones via a RuPHOX-Ru catalyzed asymmetric hydrogenation of aroylacrylic acids
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DOI: 10.1016/j.tet.2019.05.036
Abstract: Abstract An asymmetric hydrogenation of aroylacrylic acids catalyzed by RuPHOX-Ru catalyst has been developed, affording the corresponding chiral γ-lactones in high yields and with up to 93% ee. The methodology has the advantage of utilizing… read more here.
Keywords: aroylacrylic acids; asymmetric hydrogenation; hydrogenation aroylacrylic; synthesis chiral ... See more keywords