Facile access to chiral γ-butyrolactones via rhodium-catalysed asymmetric hydrogenation of γ-butenolides and γ-hydroxybutenolides
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DOI: 10.1039/d3sc00491k
Abstract: The highly efficient Rh/ZhaoPhos-catalysed asymmetric hydrogenation of γ-butenolides and γ-hydroxybutenolides was successfully developed. This protocol provides an efficient and practical approach to the synthesis of various chiral γ-butyrolactones, which are synthetically valuable building blocks of… read more here.
Keywords: butenolides hydroxybutenolides; asymmetric hydrogenation; chiral butyrolactones; catalysed asymmetric ... See more keywords