On-DNA Palladium-Catalyzed Hydrogenation-like Reaction Suitable for DNA-Encoded Library Synthesis.
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DOI: 10.1021/acs.bioconjchem.0c00566
Abstract: Herein we describe a method to orthogonally remove on-DNA N-Cbz, N-Alloc, N-Allyl, O-Bn, and O-Allyl protecting groups in the presence of other common protecting groups to afford free amines and carboxylic acids, respectively. The developed… read more here.
Keywords: dna; dna palladium; hydrogenation like; catalyzed hydrogenation ... See more keywords